A recent study by John O'Brien and colleagues focused on biomarker validation of the Cardiovascular Aging and Dementia (CAIDE) risk score in people at risk of dementia. The CAIDE score estimates 20-year dementia risk at midlife on the basis of eight variables - age, sex, education, systolic blood pressure, BMI, cholesterol level, physical activity...

Topline results from the phase 3 THALES trial show that in patients who had experienced an acute ischemic stroke or transient ischemic attack (TIA), the antiplatelet agent ticagrelor (Brilinta, AstraZeneca), in combination with aspirin, demonstrated a statistically significant reduction in the rate of repeat stroke or death compared to placebo.

Stroke and sleep apnea are highly prevalent conditions with a physiologically plausible bidirectional relationship.

Visual Snow


Visual snow is considered a disorder of central visual processing resulting in a perturbed perception of constant bilateral whole-visual field flickering or pixelation. When associated with additional visual symptoms, it is referred to as visual snow syndrome. Its pathophysiology remains elusive.

To help determine whether midlife obesity is a cause of dementia and whether low body mass index (BMI), low caloric intake, and physical inactivity are causes or merely consequences of the gradual onset of dementia by recording these factors early in a large 20-year prospective study and relating them to dementia detection rates separately during...

A recent study shows that healthy sleep patterns were associated with a reduced risk of heart disease and stroke by about one-third, even among those at high genetic risk.