In high-pollution areas, physical activity may have a paradoxical effect on brain health by increasing particulate deposition in the lungs. We examined whether physical activity modifies associations of air pollution (AP) with brain volumes in an epidemiologic framework.

Too much and too little coffee is tied to an increased risk of a specific seizure type in patients with epilepsy, new research shows (Epilepsy Behav. Published online December 17, 2021).

Just 1 to 2 hours of moderate-to-vigorous exercise twice a week appears to slow disease progression and cognitive decline in patients with early Parkinson's disease (PD), new research shows.

Post-traumatic amnesia (PTA) and chronic vascular lesions caused by traumatic brain injury (TBI) is tied to an increased risk of subsequent Alzheimer's disease (AD) (Alzheimer Disease & Associated Disorders).

Fish intake may prevent cerebrovascular disease (CVD), yet the mechanisms are unclear, especially regarding its impact on subclinical damage. Assuming that fish may have pleiotropic effect on cerebrovascular health, the authors investigated the association of fish intake with global CVD burden based on brain MRI markers...

Dimethyl fumarate (DMF) has been approved for clinical treatment of multiple sclerosis based on its antioxidant and anti-inflammatory effects by activating the Nrf2 pathway. Since both oxidative stress and inflammation are involved in Alzheimer's disease (AD), DMF is a potential therapeutic option for AD.

The authors investigated whether oral contraceptive (OC) use is associated with the risk of a second attack and disability accrual in women with a clinically isolated syndrome (CIS) and early multiple sclerosis (MS) (Mult Scler. 2021 Nov 29).