Dementia is common in Parkinson's disease (PD) but measures that track cognitive change in PD are lacking. Brain tissue iron accumulates with age and co-localises with pathological proteins linked to PD dementia such as amyloid.
A new retrospective study using linked administrative databases in Ontario, Canada, identified 97,965 adolescents (11 to 18 years old) who suffered a concussion at ⩾1 and presented to an emergency department between 1992 and 2011. Cases were matched 1:3 with people who had not suffered a concussion based on age, sex, address, and index date. The...
Playing table tennis, also known as ping-pong, appears to improve motor symptoms in patients with Parkinson's disease (PD), new research suggests.
Patients with multiple sclerosis (MS) are at increased risk for most types of infection, with the highest risk associated with renal tract infections, according to an analysis of USA Department of Defense data.
Cancer incidence rates among patients with multiple sclerosis (MS) treated after the advent of immune therapies show an increase compared with prior generations, according to a large study of Norwegian patients with MS.
Wake-Up Stroke (WUS) patients are generally excluded from thrombolytic therapy (rTPA) due to the unknown time of stroke onset. This new study published in Journal of Neurology saimed to investigate the effects of rTPA in WUS patients during every day clinical scenarios, by measuring ischemic lesion volume and functional outcomes compared to...
Remyelination following CNS demyelination restores rapid signal propagation and protects axons; however, its efficiency declines with increasing age. Both intrinsic changes in the oligodendrocyte progenitor cell population and extrinsic factors in the lesion microenvironment of older subjects contribute to this decline. Microglia and...
A new potential neuroprotectant agent has been found to be beneficial for patients with acute ischemic stroke undergoing endovascular thrombectomy in a large placebo-controlled trial, but only for those patients who did not also receive thrombolysis.
Multiple sclerosis (MS) is a multifocal inflammatory disease that involves the central nervous system and associated with limbs paralysis and serious problems in sensation, limbs, visual and sphincter. This disease is a result of autoimmune mechanism in which autoantibodies target the self-myelin antigens and cause demyelination. Because of the...
Migraine is one of the most common neurological disorders that leads to disabilities. However, the conventional drug therapy for migraine might be unsatisfactory at times. In a new meta-analysis published recently aimed to evaluate the efficacy and safety of calcitonin-gene-related peptide binding monoclonal antibody (CGRP mAb) for the preventive...
