Sugar linked to dementia

New research suggests a high-sugar diet, commonly associated with obesity, leads to insulin resistance in the brain and may heighten the risk of neurodegenerative diseases like Alzheimer's.

The study reveals that this insulin resistance impairs glial cells' ability to clear neuronal debris, a crucial process for preventing neurodegeneration.

By studying fruit flies, which share physiological similarities with humans, the team uncovered that a sugar-rich diet decreases the levels of the PI3k protein in glial cells and Draper protein in ensheathing glia, hindering their debris-clearing functions.

Source: PLOS