Obesity linked to Multiple Sclerosis and Stroke

01/04/2024

In a recent study published in Scientific Reports, researchers from China used Mendelian randomization (MR) to assess the genetic relationship between body mass index (BMI) and multiple neurological diseases.

They found that BMI shows a genetic causal relationship with multiple sclerosis (MS) and ischemic stroke (IS), but not with Parkinson's disease (PD), Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and epilepsy (EP).

The study demonstrates MR analysis's utility in exploring genetic causal links between BMI and neurological diseases.

These findings highlight obesity's potential role as a risk factor in neurological disorders, paving the way for prevention and treatment strategies for improved health outcomes.