Fungus linked to Alzheimer's disease

30/10/2023

In a new study, researches researchers explored the link between the fungus Candida albicans and Alzheimer's disease.

They found that C. albicans produces enzymes breaking down the blood-brain barrier, allowing it to access the brain and produce toxic amyloid beta-like peptides, typically associated with Alzheimer's.

These peptides activate microglial brain cells to keep fungal load low but don't clear the infection.

The study suggests that the amyloid beta aggregates in Alzheimer's could be generated both by the brain and by C. albicans.

Source: Neuroscience News