Blood test to diagnose Alzheimer's disease

25/02/2024

A simple blood test to diagnose Alzheimer's disease ( the ptau-217 blood test) soon may replace more invasive and expensive screening methods such as spinal taps and brain scans.

A study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden shows that a blood test can be as good at detecting molecular signs of Alzheimer's disease in the brain as cerebrospinal fluid tests approved by the Food and Drug Administration (FDA) for Alzheimer's diagnosis. The blood test, which was created by Washington University researchers, uses a highly sensitive technique to measure levels of Alzheimer's proteins in the blood.

The research is available Feb. 21 in Nature Medicine.

The findings demonstrate that a blood test can diagnose Alzheimer's disease pathology as accurately as cerebrospinal fluid tests and brain scans, even in patients with mild symptoms, and can be used to detect molecular signs of Alzheimer's disease in the brain when symptoms haven't yet emerged.

Source: Nature Medicine