Anti-inflammatory drugs against Alzheimer's disease

19/07/2023

A new study published in PLOS ONE sheds light on how certain anti-inflammatory drugs may prove to be effective treatments for Alzheimer's disease (AD).

The team zeroed in on a protein known as p38. Upon halting the production of this protein in brain immune cells, researchers found a decrease in the concentration of these cells around amyloid plaques—a primary AD pathology component—implying the possibility of altering interactions with AD elements.

The study suggests that long-term suppression of p38 might not cause noticeable side effects and that early inhibition could potentially change the course of AD.