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The incidence of idiopathic intracranial hypertension (IIH) - characterized by increased cerebral spinal fluid (CSF) pressure - is rising considerably, corresponding to population increases in body mass index (BMI), a new study has shown.

Heavy alcohol use in adolescence is linked to disruptions in white matter integrity, new research suggests. (JAMA Psychiatry. Published online December 30, 2020. doi:10.1001/jamapsychiatry.2020.4064)

Atabecestat, a nonselective oral β-secretase inhibitor, was evaluated in the EARLY trial for slowing cognitive decline in participants with preclinical Alzheimer disease. Preliminary analyses suggested dose-related cognitive worsening and neuropsychiatric adverse events (AEs).

Whether anti-seizure medication (ASM) increases the risk for cancer has been debated for decades. While for some ASM, a carcinoma-promoting effect has been suspected, carcinoma-protective effects have been shown for other ASM. However, the issue remains unresolved as data from preclinical and clinical studies have been inconsistent and...

Focused ultrasound for ablation of the subthalamic nucleus in one hemisphere improved motor features in a selected group of patients with markedly asymmetric Parkinson's disease, but was associated with a high rate of adverse events, including dyskinesias and other neurologic complications, in a new randomized sham-controlled trial published online...