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The incidence of idiopathic intracranial hypertension (IIH) - characterized by increased cerebral spinal fluid (CSF) pressure - is rising considerably, corresponding to population increases in body mass index (BMI), a new study has shown.

Heavy alcohol use in adolescence is linked to disruptions in white matter integrity, new research suggests. (JAMA Psychiatry. Published online December 30, 2020. doi:10.1001/jamapsychiatry.2020.4064)

Atabecestat, a nonselective oral β-secretase inhibitor, was evaluated in the EARLY trial for slowing cognitive decline in participants with preclinical Alzheimer disease. Preliminary analyses suggested dose-related cognitive worsening and neuropsychiatric adverse events (AEs).